New and Efficient Synthesis of 2-Alkoxyapomorphines

Author(s): Sandor Berenyi, Csaba Csutoras, Attila Sipos, Zsuzsanna Gyulai.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 1 , 2007

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Abstract:

A novel synthetic route has been developed for the preparation of pharmacologically remarkable (R)- (-)-2-methoxyapomorphine (2) and other 2-alkoxyapomorphines 8-10.

Keywords: 2-Alkoxyapomorphines, oripavine, acid-catalyzed rearrangement, O-demethylation, dopamine receptor binding affinity

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2007
Page: [32 - 34]
Pages: 3
DOI: 10.2174/157017807780037397

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