L-Proline as an Efficient Organo-Catalyst for the Synthesis of Polyhydroquinoline Via Multicomponent Hantzsch Reaction

Author(s): Nandkishor N. Karade, Vishnu H. Budhewar, Sandeep V. Shinde, Wamanrao N. Jadhav.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 1 , 2007

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Abstract:

L-Proline has been found as an effective catalyst for the one pot synthesis of polyhydroquinoline derivatives via four component Hantzsch reaction. This method provides several advantages such as being environmentally benign, possessing high yields with increased variations of the substituents in the product and preparative simplicity.

Keywords: Hantzsch reaction, multi-component reactions, L-proline, polyhydroquinoline, β-dicarbonyl compound, aldehyde

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2007
Page: [16 - 19]
Pages: 4
DOI: 10.2174/157017807780037405

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