Synthesis of Novel Heterocyclic Prostaglandin Analogues

Author(s): Francisco C. Biaggio , Alessandra R. Rufino , Marcela C.F. Silveira .

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 1 , 2007

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Abstract:

New prostaglandins analogues, containing heteroatoms in the cyclopentane ring were synthesized. The key step in the synthesis was the preparation of the five-membered ring starting from L-cysteine ethyl ester hydrochloride. The addition of the alkyl groups at C-15 position was also performed.

Keywords: Heterocyclic prostaglandins, azaprostaglandins, thiaprostaglandins

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2007
Page: [1 - 3]
Pages: 3
DOI: 10.2174/157017807780037388

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