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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of Novel Heterocyclic Prostaglandin Analogues

Author(s): Francisco C. Biaggio, Alessandra R. Rufino and Marcela C.F. Silveira

Volume 4, Issue 1, 2007

Page: [1 - 3] Pages: 3

DOI: 10.2174/157017807780037388

Price: $65

Abstract

New prostaglandins analogues, containing heteroatoms in the cyclopentane ring were synthesized. The key step in the synthesis was the preparation of the five-membered ring starting from L-cysteine ethyl ester hydrochloride. The addition of the alkyl groups at C-15 position was also performed.

Keywords: Heterocyclic prostaglandins, azaprostaglandins, thiaprostaglandins

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