Current Respiratory Medicine Reviews

Joseph Varon  
The University of Texas Health Science Center
Houston, TX
USA

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A Case of Fatal Community-Acquired Necrotizing Pneumonia Caused by Panton-Valentine Leukocidin Positive Methicillin-Sensitive Staphylococcus Aureus

Author(s): Narimon Honarpour, Jenny T. Mao.

Abstract:

The expression of Panton-Valentine leukocidin (PVL) has been implicated as a virulence factor for communityacquired Staphylococcus aureus pneumonia with most reported cases involving methicillin-resistant strains. Here we describe a case of community-acquired, PVL-positive methicillin-sensitive Staphylococcus aureus (MSSA) sufficiently virulent to cause rapidly progressive necrotizing pneumonia, massive pulmonary hemorrhage, sepsis, and death in a patient without conventional risk factors (diabetes, advanced age). To our knowledge, this is the first case report of a fatal necrotizing pneumonia caused by PVL-positive MSSA in Los Angeles County.

Keywords: PVL, MSSA, community-acquired necrotizing pneumonia and massive hemoptysis

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Article Details

VOLUME: 3
ISSUE: 1
Year: 2007
Page: [49 - 51]
Pages: 3
DOI: 10.2174/157339807779941776