Mini-Reviews in Medicinal Chemistry


Breath Analysis: The Approach Towards Clinical Applications

Author(s): Anton Amann, Patrik Spanel and David Smith

Affiliation: Department of Anaesthesia and General Intensive Care, Innsbruck Medical University, Anichstr. 35, A-6020 Innsbruck, Austria.


Exhaled breath analysis for clinical diagnosis and therapeutic monitoring is described with special reference to the techniques used and the underlying chemistry and physics involved. Brief outlines are given of the research carried out to date, and prospects for the future of this potentially valuable non-invasive technique are indicated.

Keywords: Breath analysis, gas chromatography, selected ion flow tube mass spectrometry, proton-transfer reaction mass spectrometry, ion mobility spectrometry, laser spectrometry

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Article Details

Page: [115 - 129]
Pages: 15
DOI: 10.2174/138955707779802606