An Expedient Approach to the Synthesis of Chloroacetic, Dichloroacetic and Acetic Acid Catalyzed by Sulfuric Acid in the Presence of Crown Ethers

Author(s): Shahnaz Perveen, Tahira B. Sarfaraz, Khalid M. Khan, Wolfgang Voelter.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 12 , 2006

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Chloroacetic (1a), dichloroacetic (2a) and acetic acid (3a) were prepared by direct transformation of trichloroethylene, tetrachloroethylene and 1,1-dichloroethylene, respectively, using sulfuric acid in the presence of catalytic amounts of crown ethers. The newly developed method increases the reaction rate by suppressing the formation of by-products, and 1a, 2a and 3a were obtained in good yields at decreased reaction temperatures and concentrations of sulfuric acid compared to conventional methods.

Keywords: Chloroacetic acid, dichloroacetic acid, acetic acid and crown ethers

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Article Details

Year: 2006
Page: [940 - 942]
Pages: 3
DOI: 10.2174/157017806779467988
Price: $65

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