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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Preparation of Heterocycles by Microwave-Induced Retro Diels-Alder Reaction

Author(s): Ferenc Miklos, Geza Stajer and Ferenc Fulop

Volume 3, Issue 12, 2006

Page: [915 - 916] Pages: 2

DOI: 10.2174/157017806779468086

Price: $65

Abstract

Pyrimidinone, thioxopyrimidinone, pyrimido[2,1-a]phthalazinone and [1,3]oxazino[2,3-a] isoindolone were obtained by means of microwave-assisted [4+2] cycloreversion. The microwave heating of the parent norbornene or oxanorbornene fused compounds in a solvent with a medium or large loss factor generates retro Diels-Alder products in excellent yield and high purity.

Keywords: Microwave, retro Diels-Alder reaction, N,N-, O,N-heterocycles


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