Convenient Preparation of Original Vinylic Chlorides with Antiparasitic Potential in Quinoline Series

Author(s): Pierre Verhaeghe, Pascal Rathelot, Sylvain Rault, Patrice Vanelle.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 12 , 2006

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Abstract:

The synthesis of various original vinylic chlorides from trichloromethylated substrates in the quinoline series is described herein. This reaction takes place under mild operating conditions via a monoelectronic transfer mechanism and presents elevated yields.

Keywords: Quinoline, antiparasitic drugs, SRN1, ERC1, vinylic chloride

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Article Details

VOLUME: 3
ISSUE: 12
Year: 2006
Page: [891 - 897]
Pages: 7
DOI: 10.2174/157017806779467997
Price: $65

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