A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O

Author(s): Javad Azizian, Ali Saffar-Teluri, Ali Asadi.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 12 , 2006

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Ultrasonic irradiation effectively promotes the 1,3-dipolar cycloaddition reaction of azomethine ylides generated from L-phenyl alanine and isatin derivatives via the decarboxylative with N-aryl maleimides in aqueous solution under stereoselective cycloaddition via endo-transition state to give new spiro pyrrolidine cycloadducts.

Keywords: Ultrasonic, 1,3-dipolar cycloaddition, spiro pyrolidines, azomethine ylides, stereoselective, endo-transition state

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Article Details

Year: 2006
Page: [887 - 890]
Pages: 4
DOI: 10.2174/157017806779468068
Price: $65

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