Synthesis and Antimicrobial Activity of Pyridine Derivatives Substituted at C-2 and C-6 Positions

Author(s): Mauro Vieira De Almeida, Marcus Vinicius de Nora Souza, Nadia Rezende Barbosa, Frederico Pittella Silva, Giovanni Wilson Amarante, Sílvia Helena Cardoso.

Journal Name: Letters in Drug Design & Discovery

Volume 4 , Issue 2 , 2007

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Abstract:

A series of C-2 and C-6 substituted pyridines was synthesized and evaluated in vitro against Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus mutans and Candida albicans. Most of compounds exhibited a wide range of modest in vitro activity against the tested microorganisms.

Keywords: Substituted pyridines, Amide, Antimicrobial activity, Synthesis

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Article Details

VOLUME: 4
ISSUE: 2
Year: 2007
Page: [149 - 153]
Pages: 5
DOI: 10.2174/157018007779422514
Price: $58

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