Adipokines and Adipocyte Targets in the Future Management of Obesity and the Metabolic Syndrome
S. Kralisch, M. Bluher, R. Paschke, M. Stumvoll and M. Fasshauer
Affiliation: Ph. -Rosenthal-Str. 27, 04103 Leipzig, Germany.
The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulinsensitizers/ insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.
Keywords: Adipokine, diabetes mellitus, insulin resistance, obesity
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