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Adipokines and Adipocyte Targets in the Future Management of Obesity and the Metabolic Syndrome

Author(s): S. Kralisch, M. Bluher, R. Paschke, M. Stumvoll and M. Fasshauer

Affiliation: Ph. -Rosenthal-Str. 27, 04103 Leipzig, Germany.

Keywords: Adipokine, diabetes mellitus, insulin resistance, obesity

Abstract:

The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulinsensitizers/ insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.

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Article Details

VOLUME: 7
ISSUE: 1
Page: [39 - 45]
Pages: 7
DOI: 10.2174/138955707779317821