Abstract
Leptin, a peptide secreted by the white adipose tissue, circulates to the central nervous system and signals the status of body energy stores, regulating feeding behavior and energy balance. As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment.
Keywords: Obesity, obesity treatment, leptin, leptin resistance, lipodystrophy
Mini-Reviews in Medicinal Chemistry
Title: Lessons from Leptins Molecular Biology: Potential Therapeutic Actions of Recombinant Leptin and Leptin-Related Compounds
Volume: 7 Issue: 1
Author(s): M. L. G. Correia and W. G. Haynes
Affiliation:
Keywords: Obesity, obesity treatment, leptin, leptin resistance, lipodystrophy
Abstract: Leptin, a peptide secreted by the white adipose tissue, circulates to the central nervous system and signals the status of body energy stores, regulating feeding behavior and energy balance. As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment.
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Cite this article as:
G. Correia L. M. and Haynes G. W., Lessons from Leptins Molecular Biology: Potential Therapeutic Actions of Recombinant Leptin and Leptin-Related Compounds, Mini-Reviews in Medicinal Chemistry 2007; 7 (1) . https://dx.doi.org/10.2174/138955707779317858
DOI https://dx.doi.org/10.2174/138955707779317858 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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