Abstract
Food intake and energy homeostasis are controlled by peripheral humoral signals, afferent neuronal pathways to the brain and central signals, represented, in particular, by neuropeptides. This review reports the status of development of novel compounds targeting some hypothalamic neuropeptide systems which are currently viewed as potential targets to treat obesity.
Mini-Reviews in Medicinal Chemistry
Title: Hypothalamic Neuropeptide Systems as Targets for Potential Anti-Obesity Drugs
Volume: 7 Issue: 1
Author(s): E. Dozio, M. Ruscica, M. Motta and P. Magni
Affiliation:
Keywords: NPY, AgRP, MCH, orexins, galanin, POMC, CART, CRH
Abstract: Food intake and energy homeostasis are controlled by peripheral humoral signals, afferent neuronal pathways to the brain and central signals, represented, in particular, by neuropeptides. This review reports the status of development of novel compounds targeting some hypothalamic neuropeptide systems which are currently viewed as potential targets to treat obesity.
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Dozio E., Ruscica M., Motta M. and Magni P., Hypothalamic Neuropeptide Systems as Targets for Potential Anti-Obesity Drugs, Mini-Reviews in Medicinal Chemistry 2007; 7 (1) . https://dx.doi.org/10.2174/138955707779317894
DOI https://dx.doi.org/10.2174/138955707779317894 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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