An Efficient and Selective End-Modification of High-Molecular Weight Poly(Ethylene Glycol)s

Author(s): Pietro Campaner, Gian Maria Bonora, Sara Drioli.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 10 , 2006

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Abstract:

An innovative procedure aimed to the production of orthogonally protected amino-derivatives of high-molecular weight poly(ethylene glycol) (PEG) modified with linkers bearing differently reactive terminal amino groups is reported. This polymeric derivative represents a convenient, new soluble support particularly suitable as a drug delivery system of mixed molecules.

Keywords: Poly(ethylene glycol), PEG, polymer, conjugates, peptide, drug delivery

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Article Details

VOLUME: 3
ISSUE: 10
Year: 2006
Page: [773 - 779]
Pages: 7
DOI: 10.2174/157017806779025942
Price: $58

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