Synthesis of Pyrido[3,2-c]coumarin Derivatives by an Intramolecular Cyclization of 4-Methyl-2-(ortho-methoxyphenyl)nicotinic Acid Using Eatons Reagent

Author(s): Yoshinobu Tagawa, Kenji Yamagata, Kunihiro Sumoto.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 10 , 2006

Abstract:

The reaction of 4-methyl-2-(methoxyphenyl)nicotinic acid with Eatons reagent (P2O5 - CH3SO3H) affords pyrido[3,2-c]coumarin derivatives or 1-methyl-4-azafluoren-9-ones depending on the position of the methoxy group on the benzene ring.

Keywords: Pyrido[3,2-c]coumarin, Eaton's reagent, methoxy group, 1-methyl-4-azafluoren-9-one, intramolecular cyclization

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Article Details

VOLUME: 3
ISSUE: 10
Year: 2006
Page: [759 - 763]
Pages: 5
DOI: 10.2174/157017806779025951
Price: $58

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