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Mini-Reviews in Medicinal Chemistry
ISSN (Print): 1389-5575
ISSN (Online): 1875-5607
VOLUME: 6
ISSUE: 10
DOI: 10.2174/138955706778560148      Price:  $58









Preservation Solutions for Solid Organ Transplantation

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Author(s): C. H. Wilson, N. R. Brook and D. Talbot
Pages 1081-1090 (10)
Abstract:
Solid organ transplantation was one of the greatest medical advances of the 20th century. Current preservation technology falls short of maintaining organs ex vivo in perpetuity. This review examines the biochemical basis of organ degradation in response to ischaemia, preservation solution composition and potential future organ preservation technology.
Keywords:
Organ transplantation, preservation solutions, machine perfusion preservation, hypothermia
Affiliation:
The Liver/ Renal Unit, The Freeman Hospital, High Heaton, Newcastle-upon-Tyne, NE7 7DN, UK.