Title: Human Beta-Defensin-3: A Promising Antimicrobial Peptide
VOLUME: 6 ISSUE: 10
Author(s):G. Batoni, G. Maisetta, S. Esin and M. Campa
Affiliation:Dipartimento di Patologia sperimentale, Biotecnologie mediche, Infettivologia ed Epidemiologia, Via S. Zeno 35-39, University of Pisa, 56127 Pisa, Italy.
Keywords:Antimicrobial peptides, human beta-defensin-3, drug resistant microorganisms, new antimicrobial drugs, peptide structure
Abstract: The field of naturally occurring antimicrobial peptides is a research area rapidly expanding due to the high potential of such molecules as new antimicrobial drugs. In this regard, the human beta-defensin-3 is particularly attractive because of its strong antibacterial activity, relative salt-insensitiveness and low toxicity for host cells.