A Novel and Convenient Method for the Synthesis of Ubiquinone-10

Author(s): Feng Wang, Xiangrui Jiang, Lihong Hu, Shengyi Dong, Xiumei Wu, Hua Bai, Yongmin Zhang, Joachim Stockigt, Yu Zhao.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 8 , 2006

Become EABM
Become Reviewer


A novel and convenient synthetic approach to ubiquinone-10 was reported via the SN2-type nucleophilic displacement reaction between copper-catalyzed Grignard reagent and the secondary allylic acetate, which was suitable for the large-scale production of ubiquinone-10.

Keywords: SN2'-type reaction, copper-catalyzed, Grignard reagent, secondary allylic acetate, regioselectivity, stereoselectivity

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2006
Page: [610 - 612]
Pages: 3
DOI: 10.2174/157017806778559464
Price: $58

Article Metrics

PDF: 1