A Novel and Convenient Method for the Synthesis of Ubiquinone-10

Author(s): Feng Wang, Xiangrui Jiang, Lihong Hu, Shengyi Dong, Xiumei Wu, Hua Bai, Yongmin Zhang, Joachim Stockigt, Yu Zhao.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 8 , 2006

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Abstract:

A novel and convenient synthetic approach to ubiquinone-10 was reported via the SN2-type nucleophilic displacement reaction between copper-catalyzed Grignard reagent and the secondary allylic acetate, which was suitable for the large-scale production of ubiquinone-10.

Keywords: SN2'-type reaction, copper-catalyzed, Grignard reagent, secondary allylic acetate, regioselectivity, stereoselectivity

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Article Details

VOLUME: 3
ISSUE: 8
Year: 2006
Page: [610 - 612]
Pages: 3
DOI: 10.2174/157017806778559464
Price: $58

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