Cytotoxicity of Native Sponges and Plants from the Colombian Caribbean Coast Against “Crown Gall” Tumors Induced by Agrobacterium tumefaciens
Eduardo de Avila.
Agrobacterium tumefaciens is a Gram-negative rod able to induce crown-gall-like tumors in the potato discs. The cytotoxicity of extracts from Tabebuia and Xetospongia spp. was evaluated using this model. Two out of the six extracts tested (dichloromethane- and partial methanol-soluble extracts of Xetospongias spp.) showed the highest biological activity.
Keywords: Tabebuia spp., Xetospongias spp., Agrobacterium tumefaciens, Ti plasmidum, Solanum tuberosum and, cytotoxicity
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