Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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Cytotoxicity of Native Sponges and Plants from the Colombian Caribbean Coast Against “Crown Gall” Tumors Induced by Agrobacterium tumefaciens

Author(s): Fredyc Diaz, Ricardo Gaitan, Delfina Urbina, Ketty Mendoza, Marta Puello, Gregorio Torres, Eduardo de Avila.

Abstract:

Agrobacterium tumefaciens is a Gram-negative rod able to induce crown-gall-like tumors in the potato discs. The cytotoxicity of extracts from Tabebuia and Xetospongia spp. was evaluated using this model. Two out of the six extracts tested (dichloromethane- and partial methanol-soluble extracts of Xetospongias spp.) showed the highest biological activity.

Keywords: Tabebuia spp., Xetospongias spp., Agrobacterium tumefaciens, Ti plasmidum, Solanum tuberosum and, cytotoxicity

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Article Details

VOLUME: 3
ISSUE: 9
Year: 2006
Page: [640 - 644]
Pages: 5
DOI: 10.2174/157018006778341129
Price: $58