Novel chiral amino-amide 9-keto-bispidines are investigated as ligands in the addition reaction of diethylzinc to aromatic aldehydes. The ligands are easily obtained by a single step procedure starting from commercially available products. Selected ligands were also supported onto different insoluble resins in order to test their activity as heterogeneous catalysts.
Keywords: diethylzinc, bispidine, 3,7-diazabicyclo[3.3.1]nonane, asymmetric synthesis, Chiral ligand
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