A Concise Total Synthesis of 7-Substituted Eudistomin Analogs

Author(s): Ryoichi Ando, Ge Li, Ji Song, Wensheng Liao, Rujian Ma, Shu-Hui Chen, Zuozhong Peng.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 6 , 2006

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Abstract:

We report herein an optimized practical synthesis of three novel 7-substituted eudistomin analogs (1-3). The total syntheses of these complex tetracyclic molecules were completed in 22 steps from the requisite 7-substituted indoles.

Keywords: demethylation, diasteroselectivity, Pictet-Spengler cyclization, total Synthesis, Eudistomin analogs

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Article Details

VOLUME: 3
ISSUE: 6
Year: 2006
Page: [455 - 458]
Pages: 4
DOI: 10.2174/157017806777828448
Price: $58

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