Reduction of N-Methoxy-N-Methylamides to the Corresponding Amines with AlCl3/LiAlH4

Author(s): Maria Caterina Viscomi, Angelo Liguori, Francesca Perri, Adolfo Le Pera, Maria Luisa Di Gioia, Antonella Leggio.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 6 , 2006

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Abstract:

Aromatic and aliphatic Weinreb amides are selectively converted into the corresponding N-methoxy- N-methylamines by treatment with lithium aluminium hydride in the presence of aluminium chloride.

Keywords: lithium aluminium hydride, aluminum chloride, reduction, Weinreb amides, N-Methoxy-N-methylamines

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Article Details

VOLUME: 3
ISSUE: 6
Year: 2006
Page: [468 - 469]
Pages: 2
DOI: 10.2174/157017806777828466
Price: $58

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