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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Adipopharmacology, a Novel Drug Discovery Approach: A Metabotrophic Perspective

Author(s): G. N. Chaldakov, M. Fiore, A. B. Tonchev and L. Aloe

Volume 3, Issue 7, 2006

Page: [503 - 505] Pages: 3

DOI: 10.2174/157018006778194835

Price: $65

Abstract

"Adipopharmacology" connotes the adipotargeting studies aimed at drug discovery. Here we focus on adipopharmacology of nerve growth factor, brain-derived neurotrophic factor, ciliary neurotrophic factor and metallothioneins. Because these factors improve glucose, lipid and antioxidant metabolism, we named them metabotrophic factors (metabotrophins).

Keywords: Adipobiology, BDNF, CNTF, Metallothioneins, Metabotrophins, NGF


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