Letters in Drug Design & Discovery

Atta-ur-Rahman  , FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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Adipopharmacology, a Novel Drug Discovery Approach: A Metabotrophic Perspective

Author(s): G. N. Chaldakov, M. Fiore, A. B. Tonchev and L. Aloe

Affiliation: Division of Cell Biology, Medical University, BG-9002 Varna, Bulgaria.

Abstract:

"Adipopharmacology" connotes the adipotargeting studies aimed at drug discovery. Here we focus on adipopharmacology of nerve growth factor, brain-derived neurotrophic factor, ciliary neurotrophic factor and metallothioneins. Because these factors improve glucose, lipid and antioxidant metabolism, we named them metabotrophic factors (metabotrophins).

Keywords: Adipobiology, BDNF, CNTF, Metallothioneins, Metabotrophins, NGF

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Article Details

VOLUME: 3
ISSUE: 7
Page: [503 - 505]
Pages: 3
DOI: 10.2174/157018006778194835
Price: $58