Adipopharmacology, a Novel Drug Discovery Approach: A Metabotrophic Perspective
G. N. Chaldakov, M. Fiore, A. B. Tonchev and L. Aloe
Affiliation: Division of Cell Biology, Medical University, BG-9002 Varna, Bulgaria.
"Adipopharmacology" connotes the adipotargeting studies aimed at drug discovery. Here we focus on adipopharmacology of nerve growth factor, brain-derived neurotrophic factor, ciliary neurotrophic factor and metallothioneins. Because these factors improve glucose, lipid and antioxidant metabolism, we named them metabotrophic factors (metabotrophins).
Keywords: Adipobiology, BDNF, CNTF, Metallothioneins, Metabotrophins, NGF
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