Synthesis and Biological Evaluation of Spirostanes Including Butyrolactone Moieties

Author(s): Carlos S. Perez, Vivian Leliebre-Lara, Odette Concepcion, Francisco Coll, Daniel G. Rivera, Orlando Pando.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 7 , 2006

Become EABM
Become Reviewer


Four new spirostanes functionalized with the butyrolactone moiety were efficiently synthesized and submitted to preliminary biological tests. Two practical synthetic routes were designed to enable the incorporation of the γ-lactone functionality into rings A and B. Butyrolactones 5 and 10 showed a promising plant growth-promoting activity which renders them good candidates for further biological studies.

Keywords: butyrolactones, biological activity, steroidal sapogenins, Steroids

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2006
Page: [519 - 522]
Pages: 4
DOI: 10.2174/157017806778341870
Price: $58

Article Metrics

PDF: 1