A One-Pot Synthesis of D-Ribonucleosides Using Natural Phosphate Doped with KI in HMDS

Author(s): Hassan B. Lazrek, Driss Ouzebla, Abdellali Rochdi, Nezha Redwane, Jean-Jacques Vasseur.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 4 , 2006

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Abstract:

Potassium iodide supported on natural phosphate in HMDS was used as a promotor in the condensation of 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose with trimethylsilylated nucleobases, under mild conditions, to provide several D-ribonucleosides.

Keywords: Natural phosphate, potassium iodide, nucleosides

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Article Details

VOLUME: 3
ISSUE: 4
Year: 2006
Page: [313 - 314]
Pages: 2
DOI: 10.2174/157017806776114531
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