Highlights in Organic Chemistry Phase Vanishing" Method-System for Diffusion Controlled Addition of Exothermic Reagents Through a Fluorous Membrane

Title: Highlights in Organic Chemistry Phase Vanishing" Method-System for Diffusion Controlled Addition of Exothermic Reagents Through a Fluorous Membrane

Volume: 3 Issue: 3

Author(s): Jernej Iskra

Affiliation:

Keywords: Friedel-Crafts Acylation, Halodehydroxylation, Bromination, fluorous phase, organic solvent, F-compounds

Abstract: Fluorous solvent in "phase-vanishing" reactions acts as a phase screen between the bulk reagent and the reaction phase. The unique properties of the fluorous phase enable the slow diffusion-controlled transport of reagent through this bulk membrane and its uniform phase-transition from transport to reaction phase. Slow addition through the whole interface prevents the build-up of localised high concentration of reagent which means that it is possible to perform reactions involving highly reactive reagents at room temperature.

Cite this article as:

Iskra Jernej, Highlights in Organic Chemistry Phase Vanishing" Method-System for Diffusion Controlled Addition of Exothermic Reagents Through a Fluorous Membrane, Letters in Organic Chemistry 2006; 3 (3) . https://dx.doi.org/10.2174/157017806775789976