Abstract
A mixture of ethyl acetoacetate and various aldehydes in the presence of ammonium salts was converted to Hantzsch ethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates under mild and green conditions with good to excellent yields.
Keywords: Hantzsch synthesis, 1,4-dihydroyridines, solvent-free conditions, green conditions, ammonium salts, ethyl 1,4-dihydro-2, 6-dimethylpyridine-3, 3,5-dicarboxylate
Letters in Organic Chemistry
Title: An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions
Volume: 3 Issue: 2
Author(s): Mohammad A. Zolfigol, Peyman Salehi and Maliheh Safaiee
Affiliation:
Keywords: Hantzsch synthesis, 1,4-dihydroyridines, solvent-free conditions, green conditions, ammonium salts, ethyl 1,4-dihydro-2, 6-dimethylpyridine-3, 3,5-dicarboxylate
Abstract: A mixture of ethyl acetoacetate and various aldehydes in the presence of ammonium salts was converted to Hantzsch ethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates under mild and green conditions with good to excellent yields.
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Cite this article as:
Zolfigol A. Mohammad, Salehi Peyman and Safaiee Maliheh, An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions, Letters in Organic Chemistry 2006; 3 (2) . https://dx.doi.org/10.2174/157017806775224288
DOI https://dx.doi.org/10.2174/157017806775224288 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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