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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions

Author(s): Mohammad A. Zolfigol, Peyman Salehi and Maliheh Safaiee

Volume 3, Issue 2, 2006

Page: [153 - 156] Pages: 4

DOI: 10.2174/157017806775224288

Price: $65

Abstract

A mixture of ethyl acetoacetate and various aldehydes in the presence of ammonium salts was converted to Hantzsch ethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates under mild and green conditions with good to excellent yields.

Keywords: Hantzsch synthesis, 1,4-dihydroyridines, solvent-free conditions, green conditions, ammonium salts, ethyl 1,4-dihydro-2, 6-dimethylpyridine-3, 3,5-dicarboxylate


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