An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions

Author(s): Mohammad A. Zolfigol, Peyman Salehi, Maliheh Safaiee.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 2 , 2006

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Abstract:

A mixture of ethyl acetoacetate and various aldehydes in the presence of ammonium salts was converted to Hantzsch ethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates under mild and green conditions with good to excellent yields.

Keywords: Hantzsch synthesis, 1,4-dihydroyridines, solvent-free conditions, green conditions, ammonium salts, ethyl 1,4-dihydro-2, 6-dimethylpyridine-3, 3,5-dicarboxylate

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Article Details

VOLUME: 3
ISSUE: 2
Year: 2006
Page: [153 - 156]
Pages: 4
DOI: 10.2174/157017806775224288
Price: $65

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