Efficient Microwave and Phosphane-Free Synthesis of Trisubstituted Olefins via Heck Coupling

Author(s): Guya Loddo, Ornella Azzolina, Andrea Magnani, Mariangela Urbano, Simona Collina.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 1 , 2006

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Abstract:

We describe an easy and convenient procedure for palladium-catalyzed Heck arylation of disubstituted olefins via microwave irradiation. This method of synthesis produces trisubstituted olefins under phosphane-free conditions and in very short times.

Keywords: microwave irradiation, chemical library, phosphane-free procedure, trisubstituted olefins, Heck reaction

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Article Details

VOLUME: 3
ISSUE: 1
Year: 2006
Page: [16 - 20]
Pages: 5
DOI: 10.2174/157017806774964549

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