Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis (Experimental Section)

Author(s): Fazal Naeem, Nida Ambreen, Khalid M. Khan, Yuan-Ping Pang, Bernadette Cusack, Elliot Richelson, Awais Anwar, Wolfgang Voelter, Javid H. Zaidi.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 1 , 2006

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Abstract:

The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

Keywords: Neurotensin, partial peptidic mimic, drug design, synthesis

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Article Details

VOLUME: 3
ISSUE: 1
Year: 2006
Page: [21 - 24]
Pages: 4
DOI: 10.2174/157017806774964530

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