A Facile Route for the Regioselective Deacetylation of Peracetylated Carbohydrates at Anomeric Position

Author(s): Srinivas Chittaboina, Blake Hodges, Qian Wang.

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 1 , 2006

Become EABM
Become Reviewer

Abstract:

The regioselective 1-O-deacetylation of peracetylated carbohydrates with ammonium acetate in DMF (or a mixed solution of tetrahydrofuran and methanol) is described. It offers a facile and efficient way to prepare O-acetylpyranosides presenting one free hydroxyl group at the anomeric position.

Keywords: Carbohydrates, regioselectivity, glycosides, acylation, glycosylations

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 3
ISSUE: 1
Year: 2006
Page: [35 - 38]
Pages: 4
DOI: 10.2174/157017806774964521

Article Metrics

PDF: 159