Current Hypertension Reviews

Prof. Kazuomi Kario
Jichi Medical University
School of Medicine
Tochigi
Japan

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An Impact of Lifestyle Modification on Insulin Resistance in Hypertensive Patients with Metabolic Syndrome

Author(s): Peera Buranakitjaroen, Meta Phoojaroenchanachai.

Abstract:

A simple instruction on the lifestyle modification study was conducted on 51 hypertensives with metabolic syndrome. Significant weight reductions from baseline, 67.7 ± 11.2 kg, was noted at the 2nd month, 66.8 ± 11.2 kg, (p < 0.01), 4th month, 66.6 ± 11.3 kg, (p < 0.01) and 6th month, 66.8 ± 11.5 kg, (p < 0.01). Decrements of insulin levels from 13.5 ± 7.3 mU/L at baseline to 12.3 ± 6.6 mU/L at the 2nd month (p = 0.075) and to 11.7 ± 6.2 mU/ L at the 4th month (p = 0.025) were observed. HOMA-IR score was also improved from 3.6 ± 2.0 at baseline to 3.2 ± 1.7 at the 2nd month (p = 0.047) and to 3.1 ± 1.8 at the 4th month (p = 0.03). However, there was no significant change in the insulin levels and HOMA-IR at the 6th month when compared to those at baseline.

Keywords: Exercise, weight reduction, metabolic syndrome, essential hypertension, Mean fasting plasma glucose, calcium channel blockers, lipid lowering, HDL-cholesterol level

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Article Details

VOLUME: 7
ISSUE: 3
Year: 2011
Page: [165 - 171]
Pages: 7
DOI: 10.2174/1573402111107030165
Price: $58