Abstract
Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.
Keywords: Apoptosis, Chemoprevention, Immunotherapy, Lead molecule, Medicinal plants, CHEMOTHERAPEUTIC, multi-cellular, Neaoplastic cells, Azadirchta Indica, metabolic engineering
Anti-Cancer Agents in Medicinal Chemistry
Title: Natural Products: Promising Resources for Cancer Drug Discovery
Volume: 12 Issue: 1
Author(s): Susmita Mondal, Santu Bandyopadhyay, Mrinal K. Ghosh, Sibabrata Mukhopadhyay, Siddhartha Roy and Chitra Mandal
Affiliation:
Keywords: Apoptosis, Chemoprevention, Immunotherapy, Lead molecule, Medicinal plants, CHEMOTHERAPEUTIC, multi-cellular, Neaoplastic cells, Azadirchta Indica, metabolic engineering
Abstract: Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.
Export Options
About this article
Cite this article as:
Mondal Susmita, Bandyopadhyay Santu, K. Ghosh Mrinal, Mukhopadhyay Sibabrata, Roy Siddhartha and Mandal Chitra, Natural Products: Promising Resources for Cancer Drug Discovery, Anti-Cancer Agents in Medicinal Chemistry 2012; 12 (1) . https://dx.doi.org/10.2174/187152012798764697
DOI https://dx.doi.org/10.2174/187152012798764697 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Role of Stem Cells in Colorectal Cancer Progression and Prognostic and Predictive Characteristics of Stem Cell Markers in Colorectal Cancer
Current Stem Cell Research & Therapy Meet Our Editorial Board Member
Current Medical Imaging Bcl-2 Inhibitors: Emerging Drugs in Cancer Therapy
Current Medicinal Chemistry Editorial [Nef: A Notorious Enigmatic Factor in HIV Biology (Guest Editor: Bruno Verhasselt)]
Current HIV Research Anti-Cancer
Current Bioactive Compounds Improvement of Chemical Stability and Activities of Anthocyanins by Complexation
Current Bioactive Compounds Chemopreventive Properties of Peptide Lunasin: A Review
Protein & Peptide Letters Monoclonal Antibodies Against Epidermal Growth Factor Receptor in Advanced Colorectal Carcinoma: Clinical Efficacy and Markers of Sensitivity&#
Reviews on Recent Clinical Trials Role of microRNAs in Chronic Lymphocytic Leukemia Pathogenesis
Current Medicinal Chemistry Prevention and Therapy of Prostate Cancer: An Update on Alternatives for Treatment and Future Perspectives
Current Drug Therapy Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability
Current Medicinal Chemistry Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications
Current Cancer Drug Targets Therapeutic Potential of Endothelial Progenitor Cells in the Field of Orthopaedics
Current Stem Cell Research & Therapy Single-chain Antibody Against Reg4 Suppresses Gastric Cancer Cell Growth and Enhances 5-FU-induced Cell Death in vitro
Anti-Cancer Agents in Medicinal Chemistry Invariant Natural Killer T Cell-Based Therapy of Autoimmune Diseases
Current Immunology Reviews (Discontinued) The Roles of Chromatin Remodeling Proteins in Cancer
Current Protein & Peptide Science Exploring Novel Immunological Interventions Using Immunoinfectomics
Anti-Infective Agents TNF as a Target of Inflammation in Rheumatoid Arthritis
Endocrine, Metabolic & Immune Disorders - Drug Targets Lactobacillus rhamnosus GG Influences Polyamine Metabolism in HGC-27 Gastric Cancer Cell Line: A Strategy Toward Nutritional Approach to Chemoprevention of Gastric Cancer
Current Pharmaceutical Design Genomic and Cellular Pathology of Lung Cancer
Current Respiratory Medicine Reviews