Employing Genetic Markers to Improve Diagnosis of Thyroid Tumor Fine Needle Biopsy

Author(s): Janete M. Cerutti.

Journal Name: Current Genomics

Volume 12 , Issue 8 , 2011

Submit Manuscript
Submit Proposal

Abstract:

Fine-Needle Aspiration (FNA) is the most widely used and cost-effective preoperative test for the initial evaluation of a thyroid nodule, although it has limited diagnostic accuracy for several types of tumors. Patients will often receive cytological report of indeterminate cytology and are referred to surgery for a more accurate diagnosis. An improved test would help physicians rapidly focus treatment on true malignancies and avoid some unnecessary treatment of benign tumors. This review will discuss current molecular markers that may improve thyroid nodule diagnosis.

Keywords: Follicular thyroid carcinoma, follicular thyroid adenoma, indeterminate nodule, FNA, molecular markers, ITM1, C1orf24, Biopsy, Genetic Markers, POINT MUTATIONS

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 12
ISSUE: 8
Year: 2011
Page: [589 - 596]
Pages: 8
DOI: 10.2174/138920211798120781
Price: $58

Article Metrics

PDF: 1