Nucleophilic Tertiary Phosphine Organocatalysts in Asymmetric Reactions

Author(s): Zhenghong Zhou, Youming Wang, Chuchi Tang.

Journal Name: Current Organic Chemistry

Volume 15 , Issue 24 , 2011

Abstract:

Phosphines have recently become popular choices as nucleophilic catalysts in many asymmetric reactions, including: diastereoselective reactions, enantioselective reactions and other special type asymmetric reactions, such as kinetic resolution and desymmetrization. This mini-review presents recent advances in the application of nucleophilic phosphine organocatalysts for the preparation of chiral building blocks.

Keywords: Desymmetrization, diastereoselective reaction, enantioselective reaction, kinetic resolution, organocatalysis, phosphine, Nucleophilic Tertiary, Asymmetric Reactions, selectivity of enzymes, enantioselective reactions, Aza-Morita-Baylis-Hillman Reaction, C-C bond-forming reaction, homologues, medicinally relevant compounds, natural products

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Article Details

VOLUME: 15
ISSUE: 24
Year: 2011
Page: [4083 - 4107]
Pages: 25
DOI: 10.2174/138527211798109222
Price: $58

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