Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia
Josep M. Argiles,
Francisco J. Lopez-Soriano,
The main aim of the present review is to summarize and evaluate the different molecular mechanisms and catabolic mediators (mainly cytokines) involved in cancer cachexia since they may represent targets for future promising clinical investigations.
Keywords: TNF-, IL-6, IL-1, TWEAK, myostatin, PIF, transcriptional factors, cancer cachexia, anorexia
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