Abstract
Studies have shown that breast conserving surgery is as efficacious as mastectomy in the treatment of women with early stage breast cancer. Recent publications, however, have demonstrated an increasing number of women electing bilateral mastectomy when diagnosed with unilateral breast cancer. Several plausible reasons for this rising trend for bilateral mastectomy include increased awareness of breast cancer risk in the contralateral breast, increased use of breast MRI as a diagnostic tool and advances in reconstructive and mastectomy techniques. This review will focus mainly on the reconstructive options within the third probable reason for the increasing trend of bilateral mastectomy, advances in breast reconstruction and mastectomy techniques. The various options in breast reconstruction will be presented with a historical perspective, as well as a brief discussion on current mastectomy techniques in breast surgical oncology, as advances in both fields have likely influenced the rising trend of bilateral mastectomy in the United States.
Keywords: Prophylactic mastectomy, breast reconstruction, implant reconstruction, autologous reconstruction, historical review
Current Cancer Therapy Reviews
Title: Breast Reconstruction – A Historical Perspective on Available Techniques for Patients Electing Bilateral Mastectomy
Volume: 7 Issue: 4
Author(s): Jonas A. Nelson, Julia Tchou, Susan Domchek, David W. Low, Joseph M. Serletti and Liza C. Wu
Affiliation:
Keywords: Prophylactic mastectomy, breast reconstruction, implant reconstruction, autologous reconstruction, historical review
Abstract: Studies have shown that breast conserving surgery is as efficacious as mastectomy in the treatment of women with early stage breast cancer. Recent publications, however, have demonstrated an increasing number of women electing bilateral mastectomy when diagnosed with unilateral breast cancer. Several plausible reasons for this rising trend for bilateral mastectomy include increased awareness of breast cancer risk in the contralateral breast, increased use of breast MRI as a diagnostic tool and advances in reconstructive and mastectomy techniques. This review will focus mainly on the reconstructive options within the third probable reason for the increasing trend of bilateral mastectomy, advances in breast reconstruction and mastectomy techniques. The various options in breast reconstruction will be presented with a historical perspective, as well as a brief discussion on current mastectomy techniques in breast surgical oncology, as advances in both fields have likely influenced the rising trend of bilateral mastectomy in the United States.
Export Options
About this article
Cite this article as:
A. Nelson Jonas, Tchou Julia, Domchek Susan, W. Low David, M. Serletti Joseph and C. Wu Liza, Breast Reconstruction – A Historical Perspective on Available Techniques for Patients Electing Bilateral Mastectomy, Current Cancer Therapy Reviews 2011; 7 (4) . https://dx.doi.org/10.2174/157339411797642579
DOI https://dx.doi.org/10.2174/157339411797642579 |
Print ISSN 1573-3947 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6301 |
Call for Papers in Thematic Issues
Current progress in Protein Degradation and Cancer Therapy
argeted Protein Degradation is gaining momentum in cancer therapy, it facilitate targeting undruggable proteins, it overcome cancer resistance and avoid undesirable side effects. Thus small molecules degraders have emerged as novel therapeutic strategy. Targeted protein degradation (TPD), the process of eliminating a protein of interest hold a great promise for ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Some Implications of Receptor Kinase Signaling Pathway for Development of Multitargeted Kinase Inhibitors
Current Radiopharmaceuticals Molecular and Genetic Bases of Pancreatic Cancer
Current Drug Targets Optimizing Tumor-Reactive γδT Cells for Antibody-Based Cancer Immunotherapy
Current Molecular Medicine 3D QSAR Pharmacophore Modeling for c-Met Kinase Inhibitors
Medicinal Chemistry Genetic Polymorphisms of Drug Metabolizing Enzymes and Transporters: The Long Way from Bench to Bedside
Current Topics in Medicinal Chemistry The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention
Anti-Cancer Agents in Medicinal Chemistry Disruption of Cell Death Signaling in Cancer: Impact on Disease Prognosis and Response to Therapy
Current Medicinal Chemistry - Anti-Cancer Agents Editorial (Thematic Issue: Applications of Peptides in Nanotechnology)
Current Topics in Medicinal Chemistry Crosstalk Signalling Role in Modulation of Drugs Side Effects
Current Molecular Pharmacology Design of Novel Antitumor DNA Alkylating Agents: The Benzacronycine Series
Current Medicinal Chemistry - Anti-Cancer Agents HGF and RhoGTPases in Cancer Cell Motility
Current Signal Transduction Therapy Alpha-1 Antitrypsin: It’s Role in Health and Disease
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cells
Current Medicinal Chemistry Evaluation of Oxidative Stress Biomarkers in Brain Metastatic and Non-Metastatic Lung Cancer Patients with Different Cell Types
Anti-Cancer Agents in Medicinal Chemistry Activating Mutations of ESR1, BRCA1 and CYP19 Aromatase Genes Confer Tumor Response in Breast Cancers Treated with Antiestrogens
Recent Patents on Anti-Cancer Drug Discovery Combination Therapy of Cisplatin and other Agents for Osteosarcoma: A Review
Current Cancer Therapy Reviews An Investigative Approach to Treatment Modalities for Squamous Cell Carcinoma of Skin
Current Drug Delivery Cellular and Physiological Effects of Ganoderma lucidum (Reishi)
Mini-Reviews in Medicinal Chemistry Fluorinated Molecules as Drugs and Imaging Agents in the CNS
Current Topics in Medicinal Chemistry Management of Early Stage Cervical Cancer
Reviews on Recent Clinical Trials