Current Diabetes Reviews

Norman E. Cameron
University of Aberdeen
Aberdeen, Scotland
UK

Back

Pharmacological Management of Type 2 Diabetes Mellitus: An Update

Author(s): Samer El-Kaissi and Suphia Sherbeeni

Affiliation: Specialized Diabetes&Endocrine Centre, King Fahad Medical City, Riyadh, Saudi Arabia.

Abstract:

While lifestyle modifications and metformin are the cornerstone of the initial management of type 2 diabetes mellitus, there is an increasing array of second and third-line pharmacological agents for this condition. These include sulphonylureas, insulin, thiazolidinediones and alpha-glucosidase inhibitors, with the more recent addition of glucagon- like peptide-1 agonists, dipeptidyl peptidase-IV inhibitors and pramlintide. Moreover, insulin analogues that better simulate endogenous insulin secretion have been developed. This review aims to provide an update on the current pharmacological management of type 2 diabetes mellitus, and to highlight the benefits and limitations of each treatment.

Keywords: Type 2 diabetes mellitus, Insulin, Thiazolidinediones, Sulphonylurea, Metformin, Glucagon-like peptide-1, Dipeptidyl peptidase-IV inhibitor, Bromocriptine, Alpha glucosidase inhibitor, Colesevelam

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

VOLUME: 7
ISSUE: 6
Page: [392 - 405]
Pages: 14
DOI: 10.2174/157339911797579160
Price: $58