The -omics Era- Toward a Systems-Level Understanding of Streptomyces
Zhan Zhou, Jianying Gu, Yi-Ling Du, Yong-Quan Li and Yufeng Wang
Affiliation: University of Texas at San Antonio, Department of Biology, One UTSA Circle, San Antonio, TX 78249, USA.
Streptomyces is a group of soil bacteria of medicinal, economic, ecological, and industrial importance. It is renowned for its complex biology in gene regulation, antibiotic production, morphological differentiation, and stress response. In this review, we provide an overview of the recent advances in Streptomyces biology inspired by -omics based high throughput technologies. In this post-genomic era, vast amounts of data have been integrated to provide significant new insights into the fundamental mechanisms of system control and regulation dynamics of Streptomyces.
Keywords: Streptomyces, genomics, systems biology, transcriptomics, proteomics, metabolomics, interactomics, antibiotics, bioinformatics, Cistromics
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