Design of Magnetic Nanoparticles-Assisted Drug Delivery System

Author(s): Guo-Jing Chen, Li-Fang Wang.

Journal Name: Current Pharmaceutical Design

Volume 17 , Issue 22 , 2011

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Abstract:

Magnetic nanoparticles (MNPs) have been designed for multifaceted applications such as contrast agents in magnetic resonance imaging (MRI) diagnosis, drug/gene carriers for different kinds of therapeutic agents, tissue repair, hyperthermia, immunoassay, and cell separation/sensing. This review highlights synthesis methods, stabilizers used for surface coating on MNPs, and target ligands for ferrying payloads to an interested disease area. Some of the recent biomedical applications of MNPs in the field of drug and DNA targeting delivery are extensively reviewed.

Keywords: Nanotechnology, magnetic nanoparticles, superparamagnetic iron oxide, surface modification, targeting therapy, drug delivery, stabilizers, sol-gel technique, Monoclonal antibodies, magnetic field

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Article Details

VOLUME: 17
ISSUE: 22
Year: 2011
Page: [2331 - 2351]
Pages: 21
DOI: 10.2174/138161211797052574
Price: $58

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