On the Scope of β-cyclodextrin-ionic Liquids Based Molecular Reactors for Free Radical Chemistry in Bio-compatible and Alternative Media

Author(s): V. Tamara Perchyonok .

Journal Name: Current Organic Chemistry

Volume 15 , Issue 17 , 2011

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Abstract:

A broad range of fundamental free radical reactions, including hydrogen and halogen atom transfer, radical deoxygenations, radical cyclization reactions, radical additions to C=C and C=N double bonds utilizing β-cyclodextrin-ionic liquid(mono-6-(1-methyl-3- imidazolium) - 6 - deoxy - β -cyclodextrin tosylate (MIM-β-CDOTs) based molecular reactors/alternative media at room temperature are investigated. The reactions proceeded smoothly in moderate to excellent yield at ambient temperature, with noticable improvements in enantioselectivity observed in several key transformations.

Keywords: Beta-cyclodextrin, ionic liquids, molecular reactors, biocompatible media, tin-free radicals chemistry, synthesis, cancer biogenesis, cellular apoptosis, homolytic cleavage, Cyclodextrins (CDs), homochiral cyclic oligosaccarides, cyclodextrins, Room Temperature Ionic liquids (RTILs), enantioselectivity, radical deoxygenations

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Article Details

VOLUME: 15
ISSUE: 17
Year: 2011
Page: [3120 - 3125]
Pages: 6
DOI: 10.2174/138527211798357155
Price: $58

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