N-Heterocyclic Carbene-Catalyzed Redox Reactions of α-Functionalized Aldehydes

Author(s): Zi-Qiang Rong , Wei Zhang , Gui-Qiu Yang , Shu-Li You .

Journal Name: Current Organic Chemistry

Volume 15 , Issue 17 , 2011

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Abstract:

This review summarizes the recent advances on the redox reactions involving α-functionalized aldehydes catalyzed by N-heterocyclic carbenes. In the presence of N-heterocyclic carbene, α-functionalized aldehydes such as α-haloaldehydes, α-ring-fused aldehydes, α-aryloxyacetaldehydes and α-aroyloxyaldehydes undergo the redox reactions affording novel reaction types.

Keywords: α-functionalized aldehydes, N-heterocyclic carbenes, organocatalysis, redox reaction, enantioselectivity, umpolung, ringexpansion, α -HALOALDEHYDES, α-RING-FUSED ALDEHYDES, Ring Expansion Reactions, α -ARYLOXYACETALDEHYDES, oxazolidinone, redox reactions, N-heterocyclic carbene (NHC), enantioselective synthesis

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Article Details

VOLUME: 15
ISSUE: 17
Year: 2011
Page: [3077 - 3090]
Pages: 14
DOI: 10.2174/138527211798357182
Price: $58

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