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Fluorescence-Functionalized Magnetic Nanocomposites as Tracking and Targeting Systems: Their Preparation and Characterizations

Author(s): Xibin Yi, Xiaodong Shen, Sheng Cui, Maohong Fan, Yongmei Li.

Abstract:

Based on the electrostatic interaction between carboxymethylated chitosan (CMCH) and negatively charged CdTe quantum dots, and the selective crosslinking of CMCH using glutaraldehyde(GA), we demonstrated the formation of Fe3O4/SiO2/CMCH/CdTe microspheres. The dense silicate shells of Fe3O4 nano-particles (NPs) protect the luminescence quenching from Fe3O4 NPs, so the composite microspheres have great fluorescence and emulative magnetism. These multifunctional fluorescence/magnetic microspheres lead to robust and water dispersible nanoparticle colloidosomes, and should be of great importance for diagnostics application and specific biological applications.

Keywords: Multifunctional Microspheres, Fe3O4/SiO2/CMCH/CdTe, Fluorescence, Magnetic, Preparation, Characterizations, Biological applications, Diagnostics application, Tracking, Targeting

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Article Details

VOLUME: 7
ISSUE: 4
Year: 2011
Page: [563 - 567]
Pages: 5
DOI: 10.2174/157341311796196781
Price: $58