In this review, the use of molecular iodine as a catalyst in the synthesis of heterocyclic compounds is presented and reviewed. In recent years, the use of molecular iodine in organic chemistry has received considerable attention because the chemical (a) is inexpensive and readily available, (b) is less toxic than alternatives, (c) has an easy workup method, and (d) is a moisture-stable, mild Lewis acid. Many of the reactions using iodine are associated with mild conditions, greater stero- and regioselectivities, short reaction times, and simplicity in their operation.
Keywords: Molecular iodine, catalyst, heterocyclic compounds, synthesis, hormones, antibiotics, alkaloids, herbicides, corrosion inhibitors, antiaging drugs, sensitizers, stabilizing agents, electropositive metallic halogen, Chilesn saltpeter, Courtois
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