The Meyers Reaction (1994-2010)

Author(s): Jacques Mortier.

Journal Name: Current Organic Chemistry

Volume 15 , Issue 14 , 2011

Abstract:

The Meyers reaction, i.e. the nucleophilic aromatic substitution reaction between aryloxazolines with organolithium and organomagnesium reagents is a very efficient and reliable method for the formation of new carbon-carbon and carbon-heteroatom bonds. The aim of this review is to present a general overview of this reaction in chiral and racemic form, emphasizing its scope and limitations. The literature is covered since 1994.

Keywords: Nucleophilic aromatic substitution, Meyers reaction, oxazolines, Grignard reagents, organolithium reagents, nucleophilic aromatic substitution reaction, aryloxazolines, organolithium, organomagnesium reagents, carbon-heteroatom bonds, racemic form, indolines, indans, tetralins, benzofurans

Rights & PermissionsPrintExport

Article Details

VOLUME: 15
ISSUE: 14
Year: 2011
Page: [2413 - 2437]
Pages: 25
DOI: 10.2174/138527211796150561
Price: $58

Article Metrics

PDF: 5
HTML: 0
EPUB: 0
PRC: 0