During the past decades Neural Stem Cells have been considered as an alternative source of cells to replace lost neurons and NSC transplantation has been indicated as a promising treatment for neurodegenerative disorders. Nevertheless, the current understanding of NSC biology suggests that, far from being mere spare parts for cell replacement therapies, NSCs could play a key role in the pharmacology of neuroprotection and become protagonists of innovative treatments for neurodegenerative diseases. Here, we review this new emerging concept of NSC biology.
Keywords: neurocytoprotective, degenerative processes, inflammationrelated processes, neurodegenerative diseases, mitochondrial dysfunction, oxidative stress, neurotrophic factors, neuroprotection, neurodegenerative disorders, Neural stem cells
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