Metal Release from and Sequestration by Metallothioneins Monitored by Electrochemistry and SPR

Author(s): Lin Liu, Jianxiu Wang.

Journal Name: Current Pharmaceutical Biotechnology

Volume 12 , Issue 5 , 2011

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Abstract:

Due to the high affinity of metallothioneins (MTs) toward various transition metal ions, MTs play an important role in regulation of essential metals, detoxification of heavy metals, and scavenging of free radicals. In this review, we focus on the recent development on the metal release from and sequestration by MTs characterized by electrochemistry and surface plasmon resonance (SPR). The investigation of metal release and coordination processes is of great significance in illustrating the intriguing role of MTs in environmental toxicology.

Keywords: Metallothionein, metal release, sequestration, electrochemistry, surface plasmon resonance

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Article Details

VOLUME: 12
ISSUE: 5
Year: 2011
Page: [847 - 852]
Pages: 6
DOI: 10.2174/138920111795470886
Price: $58

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