Current Medicinal Chemistry

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

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Protective and Therapeutic Effects of Ghrelin in the Gut

Author(s): Z. Warzecha and A. Dembinski

Affiliation: Department of Physiology, Jagiellonian University Medical College, 16 Grzegorzecka str., 31-531 Cracow, Poland.

Abstract:

Ghrelin, a peptide predominantly produced in the stomach exhibits numerous physiological functions, including stimulation of growth hormone release, food intake and gastric empting, and regulation of energy expenditure. This peptide exhibits also some protective and healing-promoting effects. This review summarizes the recent findings concerning animal and human data showing protective and therapeutic effects of ghrelin in the gut.

Keywords: Colitis, food intake, gastric ulcer, ghrelin, healing, pancreatitis, protection, physiological functions, hormone, therapeutic effects

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Article Details

VOLUME: 19
ISSUE: 1
Page: [118 - 125]
Pages: 8
DOI: 10.2174/092986712803414051