Inflammatory Response in Molluscs: Cross-Taxa and Evolutionary Considerations

Author(s): E. Ottaviani, A. Franchini, D. Malagoli.

Journal Name: Current Pharmaceutical Design

Volume 16 , Issue 38 , 2010

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Abstract:

Inflammation represents the rapid and efficient elimination of damaged tissue and microbes and eventually the restoration of tissue functionality. Inflammatory response is one of the vital reactions to body injury, acting alongside the restoration of homeostasis, wound repair and immune response. In mammals, wound healing is a process that seeks to restore tissue integrity and function, and is characterized by a series of biological processes including inflammatory response. Here, we review pioneering experiments and recent observations in invertebrate models suggesting that in highly divergent and evolutionary distant taxa, such as molluscs, insects and vertebrates, the inflammatory response could be driven by a pool of molecules sharing common evolutionary origin.

Keywords: Inflammation, invertebrates, evolution

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Article Details

VOLUME: 16
ISSUE: 38
Year: 2010
Page: [4160 - 4165]
Pages: 6
DOI: 10.2174/138161210794519084
Price: $58

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